Download PDF by Lynne E. Maquat,Megerditch Kiledjian: RNA Turnover in Eukaryotes: Nucleases, Pathways and Analysis

By Lynne E. Maquat,Megerditch Kiledjian

particular complexes of protein and RNA perform many crucial organic features, together with RNA processing, RNA turnover, RNA folding, in addition to the interpretation of genetic details from mRNA into protein sequences. Messenger RNA (mRNA) decay is now rising as a big keep an eye on aspect and an enormous contributor to gene expression. carrying on with identity of the protein components and cofactors, and mRNA instability components answerable for mRNA decay let researchers to construct a finished photograph of the hugely orchestrated approaches excited by mRNA decay and its regulation.

  • Covers the nonsense-mediated mRNA decay (NMD) or mRNA surveillance pathway
  • Expert researchers introduce the main complex applied sciences and methods to spot mRNA processing, shipping, localization and turnover, that are relevant to the method of gene expression
  • Offers step by step lab directions, together with valuable gear and reagents

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RNA Turnover in Eukaryotes: Nucleases, Pathways and Analysis of mRNA Decay: 448 (Methods in Enzymology) by Lynne E. Maquat,Megerditch Kiledjian

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